Postpartum heart failure complicated with thyroiditis: A concealed aggravator of peripartum cardiomyopathy?

We report a case of PPCM that was triggered by postpartum thyroiditis. Despite the presence of myocardial damage indicated by cardiac magnetic resonance imaging, the patient’s cardiac function completely recovered with the addition of bromocriptine to standard therapies. We discuss the role of thyroid hormones in the development of PPCM through aggravation of a prolactin-dependent anti-angiogenic effect, and we argue that more attention should be paid to postpartum thyroiditis as a novel risk factor for PPCM.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research

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ConclusionsHealth care providers should be aware of the deliberation and information-seeking in which youth engage prior to seeking care as well as the temporally misaligned decision-making processes of youth and parents. Understanding the challenges trans youth experience due to insufficient parental support and system barriers can provide important context for health care providers striving to provide accessible, gender-affirming care and decision-making support for trans youth.
Source: Journal of Adolescence - Category: Child Development Source Type: research
Publication date: Available online 20 January 2020Source: Artificial Intelligence in MedicineAuthor(s): Oh Shu Lih, V Jahmunah, Tan Ru San, Edward J Ciaccio, Toshitaka Yamakawa, Masayuki Tanabe, Makiko Kobayashi, Oliver Faust, U Rajendra AcharyaAbstractCardiovascular disease (CVD) is the leading cause of death worldwide, and coronary artery disease (CAD) is a major contributor. Early-stage CAD can progress if undiagnosed and left untreated, leading to myocardial infarction (MI) that may induce irreversible heart muscle damage, resulting in heart chamber remodeling and eventual congestive heart failure (CHF). Electrocardiog...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
CONCLUSIONS: According to the above results, our study revealed that LUCAT1 was decreased in CHF patients, which was correlated with poor prognosis of CHF patients. Furthermore, the downregulation of LUCAT1 inhibited cell proliferation and promoted cell apoptosis via targeting miR-612/HOXA13 axis. Our results elucidated a potential mechanism underlying cardiomyocyte apoptosis, which might be used as a promising prognostic marker and a potential target for CHF patients. PMID: 31957853 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CONCLUSIONS: Multi-hormonal deficiencies are associated with right ventricular dysfunction and diastolic dysfunction in patients with HFpEF. PMID: 31957849 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
We report a case in which diffusion-weighted magnetic resonance imaging (DWI) demonstrated renal artery stenosis-related renal ischemia and the therapeutic efficacy of revascularization. The patient was a 73-year-old man, who underwent descending thoracic aortic replacement due to DeBakey IIIb chronic aortic dissection, and who showed progressive renal dysfunction due to right renal artery stenosis caused by false lumen thrombosis. DWI demonstrated a decreased apparent diffusion coefficient (ADC) in the right kidney, indicating renal ischemia. Angioplasty with stenting restored renal perfusion and improved the renal functi...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
In conclusion, apart from a robust CYP response in the gill, dilbit exposure did not greatly impact common measures of seawater acclimation, suggesting that significant osmoregulatory dysfunction is unlikely to occur if Atlantic salmon smolts are exposed sub-chronically to dilbit.
Source: Aquatic Toxicology - Category: Toxicology Source Type: research
Publication date: Available online 20 January 2020Source: Respiratory Medicine Case ReportsAuthor(s): Takuma Katano, Eri Hagiwara, Hiromasa Arai, Midori Sato, Takafumi Yamaya, Michihiko Tajiri, Takashi OguraAbstractA 68-year-old man who was on treatment for pulmonary Mycobacterium avium complex complained a worsening of sputum. Although he archived negative sputum culture two months ago, sputum culture tests revealed the newly isolation of Mycobacterium abscessus repeatedly. Chest computed tomography showed newly-appeared extra-pulmonary mass lesion in contact with a cyst at the bottom of his right lung. From the results o...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Conclusions: Our study demonstrated that the rich-club reorganization in functional brain networks is characterized by switching of rich-club nodes between the high-order cognitive and sensory and motor networks during propofol-induced alteration of consciousness and natural sleep. These findings will help understand the common neurological mechanism of pharmacological and physiological unconsciousness.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Publication date: March 2020Source: Journal of Functional Foods, Volume 66Author(s): Jr-Wei Chen, Yi-Ling Lin, Chung-Hsi Chou, Yi-Hsieng Samuel Wu, Sheng-Yao Wang, Yi-Chen ChenAbstractA high-fat diet is a major risk factor for obesity and heart failure. Our previous study has demonstrated that protease A-digested crude-chalaza hydrolysates (CCH-As) with a specific free amino-acid and carnosine/anserine profile show lipid-lowering and antioxidant activities against chronic alcohol consumption. The antiobesity and hypolipidemic effects of our CCH-As against a high-fat diet was to investigated in this study. In high-fat-diet ...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
A 60-year-old woman with heart failure and no family history of cardiomyopathy/sudden death was referred to our hospital. Echocardiography revealed large pericardial effusion and thinning of akinetic right ventricular free wall (PanelsA and B). Serum biochemistry showed low level of free thyroxine with elevation of thyroid-stimulating hormone level, elevated creatinine kinase level, and positive anti-mitochondrial antibody (AMA) (M2; 13.4 U/mL). Although supplementation of thyroid hormone and administration of diuretics were started, her condition was progressively deteriorated. Repeated echocardiography revealed re...
Source: European Heart Journal - Category: Cardiology Source Type: research
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