Prophylactic treatment with MSC derived exosomes attenuates traumatic acute lung injury in rats.

In conclusion, the results provide evidence that miR-124-3p transferred by MSCs-derived exosomes inhibited P2X7 expression, thus improving OS injury and suppressing inflammatory response in traumatic ALI, highlighting a potential pretreatment for traumatic ALI. PMID: 30892077 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - Category: Cytology Authors: Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research