(400) An Ex-Vivo Human Model of Inflammatory Pain for Enabling Translational Research and Drug Discovery

The incomplete understanding of chronic neuropathic and inflammatory pain mechanisms poses a major challenge for the development of new, non-addictive pain medications. Cross-species differences in pharmacological responses and analgesic effects lead to poor translation of preclinical animal models to clinical studies in humans. We have developed methodologies for the isolation of human sensory neurons, from organ donors, which allow for ex-vivo studies of sensory neurons physiology and pharmacology.
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Industry Sponsored Posters Source Type: research