GSE128610 Crosstalk from Non-Cancerous Mitochondria Can Inbibit Tumor Properties of Metastatic Cells by Suppressing Oncogenic Pathways

Contributors : Benny Kaipparettu ; Chad Creighton ; Yiqun Zhang ; Lee-Jun WongSeries Type : Expression profiling by arrayOrganism : Homo sapiensMicroarray analysis suggested that several oncogenic pathways observed in cybrids with cancer mitochondria are inhibited in cybrids with non-cancerous mitochondria. These results suggest the critical oncogenic regulation by motochondrial-nuclear cross talk and highlights rectifying motochondiral functional properties as a promising target in cancer therapy.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE128610

Source: GEO: Gene Expression Omnibus - March 21, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research