miRNA-221 promotes cutaneous squamous cell carcinoma progression by targeting PTEN.

Conclusions: Taken together, the obtained results indicated that miR-221 plays an oncogenic function in CSCC by targeting PTEN and further suggest that miR-221 may be a potential target for CSCC diagnosis and treatment.
PMID: 30891072 [PubMed - in process]

Source: Cellular and Molecular Biology Letters - March 21, 2019 Category: Biochemistry Authors: Gong ZH, Zhou F, Shi C, Xiang T, Zhou CK, Wang QQ, Jiang YS, Gao SF Tags: Cell Mol Biol Lett Source Type: research