The effect of harmaline on seizures induced by amygdala kindling in rats.

DISCUSSION: According to the results, it is suggested that harmaline may increase neuronal activity and the production of high-frequency action potentials by stimulating NMDA receptors and inhibiting GABA receptors. Overall, drugs and plants containing harmaline may be harmful to epileptic-susceptible people during some traditionally and costume treatments, so these should be avoided.
PMID: 30890034 [PubMed - as supplied by publisher]

Source: Neurological Research - March 21, 2019 Category: Neurology Tags: Neurol Res Source Type: research