Young people on amphetamines for ADHD have twice the psychosis risk compared to other stimulants, study says

Teens and young adults with attention deficit-hyperactivity disorder, ADHD, who receive amphetamines such as Adderall for treatment have a higher risk of developing psychosis, compared to those who receive methyphenidates stimulants, such as Ritalin, according to a large new study.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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Authors: Jenabi E, Bashirian S, Khazaei S, Basiri Z Abstract This meta-analysis evaluated the association between maternal pre-pregnancy body mass index (BMI) and the risk of attention deficit hyperactivity disorder (ADHD) among children and adolescents. The search strategy was conducted until December 2018 in databases of PubMed, Web of Science and Scopus. The ORs or HRs with 95% confidence intervals (CI) extracted from eligible studies used as the common measure of association among studies. A significant association was found between overweight women and risk of ADHD among children with the pooled estimates of H...
Source: Korean Journal of Pediatrics - Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Publication date: Available online 19 June 2019Source: Pharmacology Biochemistry and BehaviorAuthor(s): Nicholas King, Samuel Floren, Natasha Kharas, Ming Thomas, Nachum DafnyAbstractMethylphenidate (MPD) is a widely prescribed psychostimulant for the treatment of attention deficit hyperactivity disorder, and is growing in use as a recreational drug and academic enhancer. MPD acts on the reward/motive and motor circuits of the CNS to produce its effects on behavior. The caudate nucleus (CN) is known to be a part of these circuits, so a lesion study was designed to elucidate the role of the CN in response to acute and chron...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
ConclusionsThese results indicate that methylphenidate increases the willingness to perform effort in individuals with ADHD, possibly due to disorder-related motivational deficits. This provides support for theories of insufficient effort allocation among individuals with ADHD.Trial registration: Clinicaltrials.gov Identifier, NCT02630017.
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
Abstract: Current research on NPs' use of the American Academy of Pediatrics (AAP) Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents is limited. This cross-sectional survey examined 89 NPs in Upstate New York regarding self-reported practice behaviors based on the guideline. Most NPs followed at least 50% of the AAP guideline for diagnosis and treatment. However, use of all criteria was less than optimal.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: NEURODEVELOPMENTAL DISORDER Source Type: research
AbstractPurpose of ReviewTo understand the impact of attention deficit hyperactivity disorder (ADHD) and its medications on blood pressure (BP) in children and adolescents and provide recommendations for management of elevated BP in children and adolescents with ADHD.Recent FindingsADHD medications have cardiovascular effects including elevated BP. However, the bulk of the evidence indicates that stimulants and other ADHD medications are safe and do not cause severe cardiovascular diseases. BP should be assessed carefully at the time of ADHD diagnosis, because some behavioral changes similar to ADHD may be associated with ...
Source: Current Hypertension Reports - Category: Primary Care Source Type: research
Publication date: Available online 17 June 2019Source: The Lancet PsychiatryAuthor(s): Chris Hollis, Qi Chen, Zheng Chang, Patrick D Quinn, Alexander Viktorin, Paul Lichtenstein, Brian D'Onofrio, Mikael Landén, Henrik LarssonSummaryBackgroundThere is a clinical concern that prescribing methylphenidate, the most common pharmacological treatment for attention-deficit hyperactivity disorder (ADHD), might increase the risk of psychotic events, particularly in young people with a history of psychosis. We aimed to determine whether the risk of psychotic events increases immediately after initiation of methylphenidate trea...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 18 June 2019Source: Journal of Psychiatric ResearchAuthor(s): Brittany R. Alperin, Christiana J. Smith, Hanna C. Gustafsson, McKenzie T. Figuracion, Sarah L. KaralunasAbstractAtypical frontal alpha asymmetry is associated with the approach/withdrawal and affective processes implicated in many psychiatric disorders. Rightward alpha asymmetry, associated with high approach, is a putative endophenotype for attention deficit/hyperactivity disorder (ADHD). However, findings are inconsistent, likely because of a failure to consider emotional heterogeneity within the ADHD population. In addition...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Attention deficit hyperactivity disorder (ADHD) is a common behavioral disorder that can occur in both children and adults. Research suggests that there may be a link between a dopamine imbalance in the brain and the development of ADHD. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: ADHD / ADD Source Type: news
Internet addiction (IA) has emerged as a public health concern, particularly among adolescents and young adults. However, few studies have been conducted in medical students. This multi-center study aimed to i...
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
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