BDNF and NGF Gene Polymorphisms and Urine BDNF-NGF Levels in Children with Primary Monosymptomatic Nocturnal Enuresis
The pathophysiology and genetic influences in nocturnal enuresis have not been fully elucidated. Delayed neuronal maturation has been suggested as a pathogenetic mechanism in primary monosymptomatic nocturnal enuresis (PMNE). Brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) are neurotrophins affecting maturation of the nervous system.
Source: Journal of Pediatric Urology - Category: Urology & Nephrology Authors: Ayd ın Ece, Salih Coşkun, Cahit Şahin, İlhan Tan, Duran Karabel, Abdullah Çim Source Type: research
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