Morning circadian misalignment is associated with insulin resistance in girls with obesity & Polycystic Ovarian Syndrome.

CONCLUSIONS: Circadian misalignment in girls with PCOS is characterized by later melatonin offset relative to both clock time and sleep timing. Findings indicate that morning circadian misalignment associates with metabolic dysregulation in girls with PCOS and obesity. Clinical care of girls with PCOS and obesity would benefit from assessment of sleep and circadian health. Further research is needed to understand mechanisms underlying the relationship between morning circadian misalignment and SI in this population. PMID: 30888398 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research