The impact of dysfunctional variants of ABCG2 on hyperuricemia and gout in pediatric-onset patients

ABCG2 is a high-capacity urate transporter that plays a crucial role in renal urate overload and extra-renal urate underexcretion. Previous studies have suggested an association between hyperuricemia and gout ...

Source: Arthritis Research and Therapy - March 20, 2019 Category: Rheumatology Authors: Blanka Stiburkova, Katerina Pavelcova, Marketa Pavlikova, Pavel Je šina and Karel Pavelka Tags: Research article Source Type: research