Identification of functional estrogen response elements in glycerol channel Aquaporin-7 gene.

CONCLUSIONS: Estrogen induces AQP7 expression by binding EREs in the promoter of the Aqp7 gene, resulting in fat catabolism of adipocyte. These results provide new insights into the molecular mechanisms underpinning the anti-adipogenic effect of estrogen.
PMID: 30888885 [PubMed - as supplied by publisher]

Source: Climacteric - March 18, 2019 Category: Geriatrics Authors: Xing L, Jin B, Fu X, Zhu J, Guo X, Xu W, Mou X, Wang Z, Jiang F, Zhou Y, Chen X, Shu J Tags: Climacteric Source Type: research