AMPK and PPAR β positive feedback loop regulates endurance exercise-mediated GLUT4 expression in skeletal muscle.

In conclusion, cooperation between AMPK and PPARβ via NRF-1/MEF2A pathway enhances the exercise training mediated adaptive increase in GLUT4 expression and subsequent glucose uptake in skeletal muscle.
PMID: 30888859 [PubMed - as supplied by publisher]

Source: Am J Physiol Endocri... - March 18, 2019 Category: Endocrinology Authors: Koh J, Hancock CR, Han DH, Holloszy JO, Nair KS, Dasari S Tags: Am J Physiol Endocrinol Metab Source Type: research