memantine (Namenda)

Title: memantine (Namenda)Category: MedicationsCreated: 11/3/2003 12:00:00 AMLast Editorial Review: 3/19/2019 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news

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Source: AARP.org News - Category: American Health Source Type: news
Publication date: Available online 15 July 2019Source: NeuroImageAuthor(s): Alex M. Pagnozzi, Jurgen Fripp, Stephen E. RoseAbstractThe deep grey matter (DGM) nuclei of the brain play a crucial role in learning, behaviour, cognition, movement and memory. Although automated segmentation strategies can provide insight into the impact of multiple neurological conditions affecting these structures, such as Multiple Sclerosis (MS), Huntington's disease (HD), Alzheimer's disease (AD), Parkinson's disease (PD) and Cerebral Palsy (CP), there are a number of technical challenges limiting an accurate automated segmentation of the DGM...
Source: NeuroImage - Category: Neuroscience Source Type: research
New research offers some of the first biological clues to why women may be more likely than men to develop Alzheimer's disease.
Source: Los Angeles Times - Science - Category: Science Source Type: news
CONCLUSIONS: CSF VGF enhances the ability of conventional biomarkers to predict MCI to AD conversion. Future work will be needed to determine the specificity of VGF for AD versus other neurodegenerative diseases. PMID: 31305322 [PubMed - as supplied by publisher]
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research
CONCLUSIONS: Amyloid-PET positivity is associated with lower MoCA scores. Clinical utility of amyloid-PET scan is likely to be suboptimal at the MoCA score cutoff for minimal cognitive impairment. PMID: 31305321 [PubMed - as supplied by publisher]
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research
CONCLUSIONS: Participants with both diabetes and at least 1 AD risk factor (ie, Obj-SCD, APOE ε4, tau, and p-tau positivity) demonstrated faster functional decline compared with those without both risk factors (diabetes or AD). These findings have implications for early identification of, and perhaps earlier intervention for, diabetic individuals at risk for future functional difficulty. PMID: 31305320 [PubMed - as supplied by publisher]
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research
Authors: Kapasi A, Yu L, Stewart CC, Schneider JA, Bennett DA, Boyle PA Abstract BACKGROUND: Low health and financial literacy may be an early behavioral manifestation of cognitive impairment, dementia, and accumulating Alzheimer pathology. However, there are limited studies investigating the behavioral features associated with hyperphosphorylated transactive response DNA-binding protein-43 (TDP-43), a common age-related pathology, and even fewer studies investigating the neurobiological basis underlying low literacy in aging. OBJECTIVE: To test the hypothesis that TDP-43 pathology is associated with lower lite...
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research
(CNN) — Having a paying job might shield women from memory loss decades later, according to a new study. That’s because paid work may offer mental stimulation, financial benefits and social connections that could limit declines in memory as women age, said Elizabeth Rose Mayeda, who led the research as an assistant professor of epidemiology at UCLA’s Fielding School of Public Health. With women making up nearly two-thirds of all Americans living with Alzheimer’s, the research suggests that preventing the disease may require more than drugs or medical interventions. “Policies that promote equal...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Stay-At-Home Moms Source Type: news
Publication date: Available online 15 July 2019Source: Chemico-Biological InteractionsAuthor(s): T.N. Pashirova, E.A. Burilova, R.G. Tagasheva, I.V. Zueva, E.M. Gibadullina, I.R. Nizameev, I.A. Sudakov, A.B. Vishtakalyk, A.D. Voloshina, M.K. Kadirov, K.A. Petrov, A.R. Burilov, S.V. Bukharov, L. Ya ZakharovaAbstractMultitarget ligands (MTL) based on sterically hindered phenol and containing a quaternary ammonium moiety (SHP-n-Q) were synthesized. These compounds are inhibitors of cholinesterases with antioxidant properties. The inhibitory selectivity is 10-fold potent for BChE than for AChE. IC50 of SHP-n-Q for BChE is 20...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Frequent use of sleep medications appears to be associated with increased long-term risk of dementia, particularly among older white adults, according to research presented at the Alzheimer's Association International Conference in Los Angeles this week.“Based on our findings, we recommend that clinicians make more effort to be aware of their patients’ sleep problems including use of sleep aids,” said lead study author Yue Leng, Ph.D., of the University of California, San Francisco, in apress release.Leng and colleagues studied 3,068 black and white community-dwelling older adults aged 70 to 79 years who ...
Source: Psychiatr News - Category: Psychiatry Tags: Association International Conference dementia Los Angeles older white adults sleep medications Source Type: research
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