New anthropometric indices in the definition of metabolic syndrome in pediatrics

Publication date: Available online 19 March 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Mostafa Fazeli, Mohammad Mohammadzadeh, Susan Darudi, Zahra Meshkat, Alireza Moslem, Hamideh Ghazizadeh, Saeeid Kargozar, Gordon Ferns, Hamidreza Bahrami-Taghanaki, Majid Ghayour-MobarhanAbstractPediatrics metabolic syndrome (MetS) may be associated with the risk of development of chronic diseases in adulthood; however, the definition of pediatric MetS is unclear, and may vary with ethnicity. The primary goal of this study was to determine the best anthropometric predictors for pediatric MetS. For this purpose, 988 high school girls were recruited. Anthropometric indices and biochemical parameters were measured using standard procedures. The adapted MetS for pediatrics, including the IDF, NCEP, and two modified-NCEPs (Cook's and DeFerranti's) were used to establish a diagnosis of MetS. Statistical analysis was performed using SPSS and MedCalc softwares. Except for body frame size (r), the values for anthropometric indices were significantly lower in an individual without MetS. Waist to height (WHtR), BMI and hip circumference (HiC) showed the strongest association with the different MetS definitions. For the IDF definition, the highest sensitivity and specificity were observed for HiC (100.0, 85.2) and WHtR (100.0, 84.7); while for the NCEP definition, the r index showed the highest sensitivity (85.0); but low specificity made it inapplicable. For the C...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research