To Sleep, Perchance to Survive?
To Sleep, Perchance to Survive?
Trends Immunol. 2019 Mar 15;:
Authors: Ransohoff RM
Abstract
Multicellular organisms exist in a sea of microbes. Survival is enabled by an immense diversity of antimicrobial peptides (AMPs) that maintain homeostasis with the microbiota. During pathogen infection, fruit fly survival varies directly with sleep. A newly-identified fruit fly sleep-regulator is also an AMP (Toda et al. Science 2019;363:509-515). Its characterization may clarify the association between sleep and surviving infection.
PMID: 30885539 [PubMed - as supplied by publisher]
Source: Trends in Immunology - Category: Allergy & Immunology Authors: Ransohoff RM Tags: Trends Immunol Source Type: research