Dosimetric properties of colloidal quantum dot-based systems for scintillation dosimetry.

Dosimetric properties of colloidal quantum dot-based systems for scintillation dosimetry. Phys Med Biol. 2019 Mar 18;: Authors: Delage MÈ, Lecavalier MÈ, Larivière D, Allen CN, Beaulieu L Abstract Colloidal quantum dots (cQDs) are starting to be used in radiation detection, either combined with an organic fluorophore or used as a sole luminescent material. In the latter case, only few studies report on cQD-based detectors for medical applications, especially for scintillation dosimetry in radiation therapy. Moreover, most of these studies focus on the effects of radiation on cQD photoluminescence but do not look into the properties of the scintillation signal itself. The present article provides a study of those cQD scintillation properties not previously investigated including the linearity of the signal as a function of dose, the signal dose rate and beam energy dependencies. The latter was also characterized for the commercially available scintillating fiber BCF-60 and liquid scintillator Ultima Gold. CdSe multishell cQDs in two physical forms were used as a sensitive dosimeter volume: a cQD powder to constitute a fiber optic based dosimeter and cQD liquid dispersions to be volumetric dosimeters. The signal linearity was assessed with a R<sup>2</sup> coefficient > 0.999 over a clinically relevant dose range at kV and MV beam energies. The cQDs had a good overall dose rate independence, with a ...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research