FDA approves Sage's first-ever treatment for postpartum depression

The FDA has approved Cambridge biopharma Sage Therapeutics' first product, a drug that the company says will be the first product specifically designed to treat postpartum depression. Zulresso is Sage's (Nasdaq: SAGE) first product to reach the market and one of two treatments the company has developed to treat postpartum depression. Its second potential therapy, an oral medication known as SAGE 217, succeeded in a late-stage trial as a postpartum treatment and is also being ev aluated as a potential…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news

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AbstractPurposeOBGYNs help patients plan families, conceive, and deliver children, however the personal reproductive history and goals, infertility experiences, and birth outcomes of OBGYNs are not well studied.  We aim to characterize female OBGYN reproductive experiences with a particular focus on infertility, reproductive life planning (methods of pregnancy prevention, reasons why pregnancy is/was delayed), birth outcomes (mode of delivery, delivery timing), and the postpartum period (breastfeeding, mat ernity leave, postpartum depression).DescriptionAn anonymous email survey was distributed to female members of Ge...
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
Publication date: July 2019Source: The Lancet Psychiatry, Volume 6, Issue 7Author(s): The Lancet Psychiatry
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Al-Haddad BJS, Jacobsson B, Chabra S, Modzelewska D, Olson EM, Bernier R, et al. Long-term Risk of Neuropsychiatric Disease After Exposure to Infection In Utero. JAMA Psychiatry 2019, in press.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Current Best Evidence Source Type: research
This study aimed to investigate the relationship between breastfeeding and postpartum depression (PPD) and it included 333 Taiwanese pregnant women. Women who had a higher score of Edinburgh Postnatal Depression Scale (EPDS) were significant older (age ≥ 35, p 
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Conclusions for PracticeThis research highlights the lack of effectiveness of existing treatment for maternal psychological distress both to benefit child development and to provide long-term symptom remediation for women. Future research could aim to identify more effective treatments for both women and children.
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
ConclusionsResults support proceeding to a definitive RCT to evaluate tDCS for antenatal depression. The preliminary efficacy estimates immediately post-treatment and in the postpartum, are encouraging with respect to the potential use of tDCS to improve treatment rates in this population. The trial was registered at: clinical trials.gov (NCT02116127).
Source: Brain Stimulation - Category: Neurology Source Type: research
An expert in perinatal psychopharmacology describes how this novel drug works in the management of postpartum depression, and the challenges posed by its safety requirements.Medscape Ob/Gyn
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Commentary Source Type: news
Publication date: Available online 20 June 2019Source: NeuroscienceAuthor(s): Matteo Di Segni, Diego Andolina, Sebastian Luca D’Addario, Lucy Babicola, Donald Ielpo, Alessandra Luchetti, Tiziana Pascucci, Luisa Lo Iacono, Francesca R. D'Amato, Rossella VenturaAbstractAlterations in early environmental conditions that interfere with the creation of a stable mother-pup bond have been suggested to be a risk factor for the development of stress-related psychopathologies later in life. The long-lasting effects of early experiences are mediated by changes in various cerebral circuits, such as the corticolimbic system, whic...
Source: Neuroscience - Category: Neuroscience Source Type: research
Postpartum depression (PPD) is a major depressive disorder that occurs after childbirth. Objective diagnostic and predictive methods for PPD are important for early detection and appropriate intervention. DNA ...
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
ConclusionThis project demonstrated that with planning, systems review and trained staff, PPD screening can be integrated into obstetric and pediatric practices and high screening and referral rates can be achieved.
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
More News: American Health | Depression | Health Management | Postnatal Depression