Association of HLA-B27 and Behcet ’s disease: a systematic review and meta-analysis

ConclusionsThere is a significant correlation between HLA-B27 and Behcet ’s Disease, but it was weak. Environmental and genetic factors might determine which the “HLA-B27” alleles manifest Behcet’s disease progression. Future researches is required to perform about what factors can do to positively and separately influence Behcet’s disease.
Source: Autoimmunity Highlights - Category: Allergy & Immunology Source Type: research

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CONCLUSIONS: Hypokalemia was more common compared to glomerulotoxicity and acute renal injury (according to KDIGO and RIFLE criteria) in pediatric leukemia patients treated with L-AmB. Hypokalemia developed in nearly half of the patients and the study shows the need for randomized controlled trials and strategies for hypokalemia associated with L-AmB treatment.PMID:34535406 | DOI:10.1016/j.nephro.2021.06.007
Source: Nephrologie and Therapeutique - Category: Urology & Nephrology Authors: Source Type: research
Conditions:   Oral Ulcer;   Behcet Syndrome Intervention:   Drug: Tacrolimus ointment Sponsor:   Assiut University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: In this study, with a threshold P-value of 0.05 and an estimated power of 0.81 to detect a significant association (odds ratio ≥1.2), we did not observe any association of this variant with Behcet's disease.PMID:34459335 | DOI:10.1080/02713683.2021.1963785
Source: Current Eye Research - Category: Opthalmology Authors: Source Type: research
Source: International Journal of General Medicine - Category: General Medicine Tags: International Journal of General Medicine Source Type: research
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