Identifying CYR61 as a Potential Anti ‐fibrotic and Pro‐angiogenic Mediator in Scleroderma

ConclusionsWe identified CYR61, which is epigenetically regulated by HDAC5, as a potent anti ‐fibrotic and pro‐angiogenic mediator in SSc. Therapeutic intervention to promote CYR61 activity or increase CYR61 levels might be of potential benefit in SSc.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatology - March 17, 2019 Category: Rheumatology Authors: Pei ‐Suen Tsou, Dinesh Khanna, Amr H. Sawalha Tags: Full Length Source Type: research