Short-term metabolic adjustments in Plasmodium falciparum counter hypoxanthine deprivation at the expense of long-term viability

The malarial parasite Plasmodium falciparum is an auxotroph for purines, which are required for nucleic acid synthesis during the intra-erythrocytic developmental cycle (IDC) of the parasite. The capabilities of ...

Source: Malaria Journal - March 19, 2019 Category: Infectious Diseases Authors: Shivendra G. Tewari, Krithika Rajaram, Patric Schyman, Russell Swift, Jaques Reifman, Sean T. Prigge and Anders Wallqvist Tags: Research Source Type: research