Involvement of cutaneous SR-B1 in skin lipid homeostasis.

CONCLUSION: We conclude that one of the main functions of SR-B1 in the skin is to regulate ceramide levels and thereby maintain the barrier function of the skin, resulting in the protection of cutaneous tissues from outdoor insults.
PMID: 30876920 [PubMed - as supplied by publisher]

Source: Archives of Biochemistry and Biophysics - March 11, 2019 Category: Biochemistry Authors: Maria MX, Marie-Sophie N, Woodby B, Ferrara F, Florian G, Giuseppe V Tags: Arch Biochem Biophys Source Type: research