Percutaneous coronary intervention for a Chinese familial hypercholesterolemia homozygous under the guidance of optical  coherence tomography.

In this study, a Chinese male HoFH received percutaneous coronary intervention for unstable angina. After analyzed his genetic and follow-up data, OCT was performed during interventional therapy. Multiple lipid rich plaques accompanied with inflammatory cell infiltration and a thin-cap fibroatheroma(TCFA) were noted, which reflected the vulnerability of plaques. The utility of OCT had certain guiding significance for strategy of interventional therapy and the long-term drug management. And this case suggested that it was important to undergo OCT examination for patients with HoFH who required percutaneous coronary intervention.
PMID: 30876528 [PubMed - in process]

Source: Atherosclerosis Supplements - February 28, 2019 Category: Cardiology Authors: Liu Z, Peng J, Wang S, Jiang T, Zhang W, Zhang C, Chen Y, Meng K, Lin J Tags: Atheroscler Suppl Source Type: research