Cognitive functions and social cognition in multiple sclerosis: An overview.
Cognitive functions and social cognition in multiple sclerosis: An overview.
Hell J Nucl Med. 2019 Jan-Apr;22 Suppl:102-110
Authors: Giazkoulidou A, Messinis L, Nasios G
Abstract
Cognitive decline has been widely reported in patients with multiple sclerosis (MS) despite its clinical heterogeneity, at all stages and in all subtypes of the disease. Deficits are most commonly present in attention, processing speed, working memory, verbal fluency and executive function. However, MS patients also show decreased performance in tasks related to social cognition, i.e. mental operations thatdrive interpersonal skills such as social perception, empathy and theory of mind. Social cognitive deficits are an underestimated but important aspect of impairment in MS, reflecting how people process, store, and apply information in social interactions. Deficits in these domains have been associated with reduced social and psychological quality of life, even after controlling for severity and duration of the disease, age, and neurocognitive performance. Social cognition impairment is not entirely dependent on and parallel to general cognitive dysfunction, given that some patients experience disorganization of their social life before a significant or detectable cognitive impairment. The decrease in performance of social cognition tasks may reflect changes in brain activity and brain structure, either general or regional. Both subtle diffuse pathology and...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
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