Muscle Fiber Splitting Is a Physiological Response to Extreme Loading in Animals

Skeletal muscle fiber branching and splitting typically is associated with damage and regeneration and is considered pathological when observed during loading-induced hypertrophy. We hypothesize that fiber splitting is a nonpathological component of extreme loading and hypertrophy, which is primarily supported by evidence in animals, and propose that the mechanisms and consequences of fiber splitting deserve further exploration.

Source: Exercise and Sport Sciences Reviews - March 16, 2019 Category: Sports Medicine Tags: Articles Source Type: research