Application of SRMS 154 as sustained release matrix for the delivery of stavudine: In vitro and in vivo evaluation and effect of Poloxamer 188 on the properties of the tablets.

CONCLUSION: Stavudine SRMS-based tablets had good stability and sustained release properties. Formulations containing 1 % Poloxamer 188 exhibited enhanced in vivo absorption and hence could be used once daily in order to enhance the bioavailability of this drug. PMID: 30868966 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30868966?dopt=Abstract

Source: Infectious Disorders Drug Targets - March 12, 2019 Category: Infectious Diseases Authors: Chime SA, Attama AA, Onunkwo GC Tags: Infect Disord Drug Targets Source Type: research

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