Distinct Heart Failure Phenotypes Identified by Myocardial Transcriptome Sequencing: Targets for Reverse Remodeling

Systolic heart failure (HF) is a progressive disease characterized by adverse remodeling from ischemia (ischemic cardiomyopathy, ICM) or a multitude of other causes termed non-ischemic cardiomyopathy (NICM). To accurately characterize the myocardial transcriptome in advanced HF using RNA-sequencing (RNAseq) and identify gene signatures that predict HF phenotypes.

Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: P. Shah, W. Zhu, S. Navankasattusas, D.K. Ramadurai, S.S. Desai, I. Taleb, I. Efimov, R. Singh, N. Aliyev, R.K. Iyer, O. Wever-Pinzon, S. McKellar, W.T. Caine, C.R. deFilippi, J. Zhu, S. Drakos Tags: 6 Source Type: research