Predictive Biomarkers for Bronchiolitis Obliterans

Chronic Allograft Dysfunction (CLAD) with Bronchiolitis obliterans (BOS) phenotype is a major limitation for long term survival after lung transplantation (LT). Predictive biomarkers for BOS are unavailable. Purpose of our study was to establish a tractable system to evaluate the effects of pre-transplant antibodies to self-antigens (AutoAbs) and to examine specific patterns that correlate with BOS.

Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: V. Kaza, C. Zhu, L. Feng, A. Reddy, C. Lacelle, L. Terada, M. Manish, S. Bollineni, A. Banga, F. Torres, J. Mullins, Q. Li Tags: 14 Source Type: research