Endomyocardial Biopsy Findings in Pediatric Heart Transplants Recipients with Positive HLA Associated Antibodies: Review of a Cohort with Poor Outcomes

Antibody mediated rejection (AMR) continues to be a major complication after heart transplantation (OHT) and poses a risk for allograft failure, graft vasculopathy and mortality. Diagnostic criteria for AMR have evolved over the years. Incidence of AMR is estimated to be 11-20% after OHT. We sought to evaluate the histological characteristics of AMR in endomyocardial biopsies (EMB) of deceased pediatric patients with positive HLA-associated antibodies.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 119 Source Type: research