Characteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis

In the setting of Cardiogenic Shock (CS), impaired biventricular function can lead to an acute decrease in renal function via reduced renal perfusion and increased renal venous pressure. In a nationally representative sample, we sought to analyze the characteristics and outcomes of patients hospitalized with CS requiring renal replacement therapy (hemodialysis) for acute kidney injury (AKI-HD).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 132 Source Type: research

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This article discusses patient assessment and management with anticoagulation, sedation, ventilation, and nutrition. Complications may occur, including bleeding, hemolysis, infection, acute kidney injury, stroke, left ventricular distention, limb ischemia, and upper body hypoxia. Patients may recover enough myocardial function to be weaned from ECMO or may be transitioned to a ventricular assist device or transplant. Quality of life may be affected by VA ECMO but may be no different than patients with other chronic health issues.
Source: Critical Care Nursing Clinics of North America - Category: Nursing Authors: Source Type: research
In this study they also showed PTX3 localized in NETs formed after neutrophil activation (5). Proteomics analysis revealed that PTX3 forms complexes with two anti-microbial proteins [azurocidin (AZU1) and myeloperoxidase (MPO)] associated to NETs (30). More recently, PTX3 localization in NETs has been confirmed, and the colocalization with AZU1 and MPO has been defined more accurately (31). Further investigation will be needed to understand the involvement of PTX3 interaction with AZU1 and MPO in their antibacterial role during NET formation. Regulation of Complement Activation PTX3 interaction with microorganisms is not...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is commonly used in patients with severe cardiogenic shock. However, left ventricular unloading may be impaired due to an increase in afterload caused by VA-ECMO. Impella has surged as an unloading device in this scenario but, its concomitant use with VA-ECMO has been associated with a higher risk of bleeding, hemolysis and acute kidney injury (AKI) requiring renal replacement therapy (RRT) in these patients.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 408 Source Type: research
The Model of End-Stage Liver Disease (MELD) score incorporates measures of kidney and liver dysfunction. MELD score has been shown to predict mortality in patients with advanced heart failure or cardiogenic shock (CS). Prior small single-center studies have shown that MELD score predicts mortality in patients supported with Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO). The Purpose of our was to reassess the role of MELD score predicting Mortality After (VA-ECMO).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 1099 Source Type: research
Abstract A 44-year-old male with ongoing chest pain and left ventricular ejection fraction 400 s: multiple argatroban bolus doses were required, along with accelerated up-titration of infusion dosing. Despite maintaining an ACT>484 s, clot formation was observed in the cardiotomy reservoir prior to separation. Subsequently, the patient developed severe disseminated intravascular coagulopathy, with both intra-cardiac and intravascular thrombi, requiring massive transfusion and continuous cell saving due to severe hemorrhage post cardiopulmonary bypass (CPB). The patient received a total of 105 units of plasma, 7...
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
Heart transplantation (HT) recipients represent a growing patient population. Though mechanisms might differ, coronary artery disease is an important cause of morbidity in this group. Limited data are available on the outcomes of Acute myocardial infarction (AMI) in HT in comparison to general population (non-HT). The study population was extracted from the National Readmissions Data 2014 using International Classification of Diseases, Ninth Revision, Clinical Modification codes for AMI and HT. The study outcomes included in-hospital all-cause mortality, length of hospital stay (LOS), cardiogenic shock, acute kidney injury...
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Salna et  al1 described 192 patients who underwent venoarterial extracorporeal membrane oxygenation, 31 (16%) of whom developed cannulation-associated lymphocele formation. Of those with lymphoceles, 13 (42%) required surgical incision and drainage; 4 (31%) patients required repeated surgical intervention. Salna et al highlighted the prevalence of lymphoceles, which have been associated with abdominal and pelvic dissection, radical prostatectomy, kidney transplantation, lumbar fusion, resection of gynecologic malignant neoplasms, and heart transplantation.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Letter to the Editor Source Type: research
ANISH KOKA MD In an age where big data is king and doctors are urged to treat populations, the journey of one man still has much to tell us. This is a tale of a man named Joe. Joseph Carrigan was a bear of a man – though his wife would say he was more teddy than bear.  He loved guitar playing,  and camp horror movies.  Those who knew him well said he had a kind heart, a quick wit and loved cats. I knew none of these things when I met Joe in the Emergency Department on a Sunday afternoon.  I had been called because of an abnormal electrocardiogram – the ER team was worried he could be having ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: blogs
ANISH KOKA MD In an age where big data is king and doctors are urged to treat populations, the journey of one man still has much to tell us. This is a tale of a man named Joe. Joseph Carrigan was a bear of a man – though his wife would say he was more teddy than bear.  He loved guitar playing,  and camp horror movies.  Those who knew him well said he had a kind heart, a quick wit and loved cats. I knew none of these things when I met Joe in the Emergency Department on a Sunday afternoon.  I had been called because of an abnormal electrocardiogram – the ER team was worried he could be having ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Cardiac surgery High-risk Quality Reporting Source Type: blogs
Authors: Kim EJ, Chang S, Kim SY, Huh KH, Kang S, Choi YS Abstract Patients with end-stage renal disease (ESRD) show characteristic abnormalities in cardiac structure and function. We evaluated the influence of these abnormalities on adverse cardiopulmonary outcomes after living donor kidney transplantation in patients with valid preoperative transthoracic echocardiographic evaluation. We then observed any development of major postoperative cardiovascular complications and pulmonary edema until hospital discharge. In-hospital major cardiovascular complications were defined as acute myocardial infarction, ventricula...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
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