Long-Term Outcomes in Pulmonary Arterial Hypertension by Functional Class: A Meta-Analysis of Randomized Controlled Trials and Observational Registries

Patients with World Health Organization (WHO) functional class (FC) I/II pulmonary arterial hypertension (PAH) are often considered to be patients whose disease is controlled. However, little is known about their prognosis compared with patients with WHO FC III/IV disease. This meta-analysis evaluated survival outcomes in observational registries by FC, and compared treatment effects observed in randomized controlled trials (RCTs) by FC.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 215 Source Type: research