The Evolving Long-Term Outcome of Heart Transplantation in Amyloid Patients

Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid are expanding indications for heart transplantation (HTx). In the past, AL amyloid, in particular, had been a contraindication to HTx given its systemic nature and the increased risk for mortality. Modern treatments including proteasome inhibitors have allowed amyloid patients to receive heart transplants at an increasing rate. We sought to assess long-term post-transplant outcome in amyloid patients in the current era.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 515 Source Type: research