Reconsidering Indication of Lung Transplantation for Late-Onset Noninfectious Pulmonary Complications after Hematopoietic Stem Cell Transplantation

Late-onset noninfectious pulmonary complications (LONIPCs) after hematopoietic stem cell transplantation (HSCT) may occur within 2 years after HSCT. Its prognosis is still poor with a survival rate of less than 20 % at 5 years after its diagnosis, and early lung transplantation (LT) may be required in some cases. However, according to the current international guideline, the time interval between HSCT and LT must be more than 5 years for patients with a history of hematologic malignancy. It should be also noted that blood type may be changed at the time of HSCT, however, ABO-incompatible lung transplantation is contraindicated in general.

Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: M. Noguchi, T.F. Chen-Yoshikawa, H. Kayawake, Y. Yamada, Y. Yutaka, D. Nakajima, M. Hamaji, A. Ohsumi, H. Date Tags: 537 Source Type: research