Time in Therapeutic Range Using Bivalirudin for Pediatric Ventricular Assist Devices

The optimal antithrombosis regime for children on ventricular assist devices (VADs) is controversial and the neurologic event rate remains unacceptably high. Bivalirudin, a direct thrombin inhibitor (DTI), may confer advantages over unfractionated heparin but has not been well-studied in this population. The primary aim of this study was to describe the percent time in therapeutic range for activated partial thromboplastin time (aPTT) using bivalirudin in a cohort of children on VADs.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 1214 Source Type: research