Is Schimmelpenning Syndrome Associated with Intracranial Tumors? A Case Report

We report a case of an adolescent boy with Schimmelpenning syndrome with a multifocal pilocytic astrocytoma. NoHRAS orKRAS gene mutations were noted in the tumor on genetic sequencing. However, glial tumors have been associated with genetic mutations of RAS upregulation, which may imply a common pathway.Pediatr Neurosurg
Source: Pediatric Neurosurgery - Category: Neurosurgery Source Type: research