Uganda: Concern As HIV Cases Soar in Oil-Rich Districts

[Monitor] Hoima -Communities in Hoima and Kikuube districts where commercially viable oil resources have been discovered are grappling with the HIV/Aids pandemic.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Publication date: December 2019Source: Microbial Pathogenesis, Volume 137Author(s): Faruq Abdulla, Utpal Kumar Adhikari, M. Kamal UddinAbstractTill now, AIDS, caused by the human immunodeficiency virus (HIV) is still a severe health problem worldwide. It weakens the immune system by targeting the T-helper cells. Specifically, the severity of the pandemic HIV-1 makes the emergence of an enduring effective vaccine against HIV-1. Therefore, we have applied a series of immunoinformatics approaches to the four conserved domains of HIV-1 integrase (IN) proteins to design an effective multi-epitope based subunit vaccine which mig...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
This study uses qualitative data from 20 in-depth interviews and one focus group to examine the risk behaviours of university students aged 18-24 years old, with particular emphasis on understanding the decline in the use of condoms. It is well documented that South Africa has one of the highest prevalence rates of HIV and AIDS in the world, however the findings of this study suggest that even though students were well informed about the perceived risks associated with unsafe sexual behaviours, they continue to engage in risk behaviours including unprotected sexual intercourse, multiple sexual partners and the use of alcoh...
Source: African Journal of AIDS Research - Category: African Health Tags: Afr J AIDS Res Source Type: research
By The Editorial Team, IntraHealth InternationalSeptember 13, 2019Over the course of our 40-year history, IntraHealth International has consistently designed creative solutions to health workforce challenges. From new technologies to old-fashioned human storytelling, we find new solutions to longstanding problems.  In a new technical publication, we highlight seven examples of how and why we look for new ways to get results. Here’s a sneak peak of what’s inside The Future of Global Health Starts Here: 7 Creative Approaches to Health Workforce Challenges. Funding the Nex...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Family Planning & Reproductive Health HIV AIDS Noncommunicable Diseases Digital Health Education Performance Policy Advocacy Health Workforce Systems Health Workers Source Type: news
Seminal amyloid fibrils are made up of naturally occurring peptide fragments and are key targets for the development of combination microbicides or antiviral drugs. Previously, we reported that the polysulfonic compound ADS-J1 is a potential candidate microbicide that not only inhibits HIV-1 entry, but also seminal fibrils. However, the carcinogenic azo moieties in ADS-J1 preclude its clinical application. Here, we screened several ADS-J1–like analogs and found that the antiparasitic drug suramin most potently inhibited seminal amyloid fibrils. Using various biochemical methods, including Congo red staining, CD analy...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Microbiology Source Type: research
Histoplasmosis is a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum, with disseminated histoplasmosis (HD) being one of its clinical forms. As a consequence of the HIV-AIDS pandemic, HD has become prevalent not only in regions that are recognized as endemic but also in areas not considered endemic, such as Europe and Asia. Its clinical manifestations are varied and mimic several infectious diseases, mainly tuberculosis. In endemic areas, it is the first manifestation of AIDS in 50 to 70% of patients. The diagnosis of histoplasmosis is difficult and HD can lead to death if not diagnosed early and if p...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
Two HIV virus types exist: HIV-1 is pandemic and aggressive, whereas HIV-2 is confined mainly to West Africa and less pathogenic. Despite the fact that it has been almost 40 years since the discovery of AIDS, ...
Source: AIDS Research and Therapy - Category: Infectious Diseases Authors: Tags: Review Source Type: research
es SL, Wejse C Abstract Two HIV virus types exist: HIV-1 is pandemic and aggressive, whereas HIV-2 is confined mainly to West Africa and less pathogenic. Despite the fact that it has been almost 40 years since the discovery of AIDS, there is still no cure or vaccine against HIV. Consequently, the concepts of functional vaccines and cures that aim to limit HIV disease progression and spread by persistent control of viral replication without life-long treatment have been suggested as more feasible options to control the HIV pandemic. To identify virus-host mechanisms that could be targeted for functional cure d...
Source: AIDS Research and Therapy - Category: Infectious Diseases Authors: Tags: AIDS Res Ther Source Type: research
CONCLUSIONS: STIs remain pandemic, and the availability of ART may have led to an increase in STIs, as fear of HIV has diminished. Classical STIs present a huge worldwide health burden that cannot be separated from HIV, and they deserve far more attention than they currently receive. PMID: 31468737 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Abstract Histoplasmosis is a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum, with disseminated histoplasmosis (HD) being one of its clinical forms. As a consequence of the HIV-AIDS pandemic, HD has become prevalent not only in regions that are recognized as endemic but also in areas not considered endemic, such as Europe and Asia. Its clinical manifestations are varied and mimic several infectious diseases, mainly tuberculosis. In endemic areas, it is the first manifestation of AIDS in 50 to 70% of patients. The diagnosis of histoplasmosis is difficult and HD can lead to death if not diagno...
Source: Dermatol Online J - Category: Dermatology Authors: Tags: Dermatol Online J Source Type: research
This study aims at exploring the global and historical evolution of literature and suggesting the most frequent research topics and research gaps in relation to the use of HBT in HIV/AIDS. A cross-sectional analysis of global HIV/AIDS bibliography was conducted through Web of Science (WoS) up to December 31, 2017. We utilized exploratory factor analysis to test the likelihood of research domains and landscape from the abstracts. A total of 29,997 papers in 153 HIV-related research areas were retrieved from the WoS database. This study suggests that HIV/AIDS research based on HBTs is increasing, and mainly focuses on elucid...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
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