Serum bone markers in ROD patients across the spectrum of decreases in GFR: Activin A increases before all other markers 
.

CONCLUSION: Serum activin A levels increase starting at CKD 2 before elevations in intact PTH and FGF-23. Activin A correlates with bone turnover similar to intact PTH and FGF-23. These findings suggest a role for activin A in early development of ROD.
.
PMID: 30862350 [PubMed - as supplied by publisher]

Source: Clinical Nephrology - March 12, 2019 Category: Urology & Nephrology Authors: Lima F, Mawad H, El-Husseini AA, Davenport DL, Malluche HH Tags: Clin Nephrol Source Type: research