Rheumatoid arthritis: Choline kinase—more than a cancer therapy target?

Nature Reviews Rheumatology 10, 699 (2014). doi:10.1038/nrrheum.2014.180 Author: Nicholas J. Bernard “Blocking choline kinase suppressed the aggressive behavior of fibroblast-like synoviocytes in rheumatoid arthritis and was highly effective in a preclinical model of arthritis,” says Monica Guma, corresponding author of a study published in Annals of the Rheumatic Diseases.Choline kinase is a phosphotransferase enzyme

http://feeds.nature.com/~r/nrrheum/rss/current/~3/5mAVzoMG7XY/nrrheum.2014.180

Source: Nature Reviews Rheumatology - October 21, 2014 Category: Rheumatology Authors: Nicholas J. Bernard Tags: Research Highlight Source Type: research