Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis

Liver disease develops in 15% –72% of patients with cystic fibrosis, and 5%–10% develop cirrhosis or portal hypertension, usually during childhood. Transient elastography (TE) is a noninvasive method to measure liver stiffness. We aimed to validate its accuracy in detection of liver disease and assessment of fibrosis in chil dren with cystic fibrosis.

Source: Clinical Gastroenterology and Hepatology - March 13, 2019 Category: Gastroenterology Authors: Peter J. Lewindon, Mora V. Puertolas-Lopez, Louise E. Ramm, Charlton Noble, Tamara N. Pereira, Julie A. Wixey, Gunter F. Hartel, Diego A. Calvopina, Daniel H. Leung, Grant A. Ramm Source Type: research