Risk prediction model boosts accuracy of CT lung screening
Researchers from the University of Pittsburgh developed a statistical model...Read more on AuntMinnie.comRelated Reading: AI reliably characterizes pulmonary nodules on CT AI spots lung nodules on CT, with low false-positive rate New AI algorithm identifies small lung tumors on CT scans Risk-based CT lung screening could be more efficient Lung cancer risk model optimizes follow-up CT screening
A 79-year-old woman with a history of anxiety, depression, and chronic obstructive pulmonary disease, as well as a remote history of breast cancer treated with lumpectomy and radiation, presented to her primary care physician with new right upper quadrant abdominal pain. Abdominal ultrasound identified 3 liver lesions, with MRI confirmation. Computed tomography–guided liver biopsy identified a diagnosis of small cell carcinoma, positive for synaptophysin and chromogranin. Positron emission tomography/computed tomography identified a 3.3- cm left hilar mass with mediastinal lymphadenopathy and concern for lympha...
A low-dose CT scan is the standard diagnostic test for people at high risk of lung cancer. In the United States, about one-quarter of these scans reveal shadows indicating nodules in the lung. Despite that positive result, fewer than 4 percent of those patients actually have cancer.
Conclusions: In patients with early-stage nsclc treated with sabr, mtv appears to be prognostic of lc and os. PMID: 30853810 [PubMed - in process]
Abstract Diffusion-weighted magnetic resonance imaging (DWI) has been reported to be useful for the assessment of lung cancer staging. It is uncertain whether DWI is more accurate for the response evaluation of chemotherapy and/or radiotherapy compared to computed tomography (CT). The purpose of this study is to compare the response evaluation of DWI for chemotherapy and/or radiotherapy to recurrent tumors of lung cancer with that of CT which is a standard tool in RECIST (Response Evaluation Criteria in Solid Tumours). Forty-one patients who agreed to this project and had CT scan and DWI examinations within a mont...
ConclusionsSignificant associations emerged between PET features, CT features, and histological type in NSCLC. Texture analysis on PET/CT shows potential to differentiate between histological types in patients with non-small-cell lung cancer.
CONCLUSION: The present investigation demonstrates that the image-based manual determination of BSUV in the aorta is sufficiently reproducible across different observers and delineation tools which is a prerequisite for accurate SUR determination. This finding is in line with the already demonstrated superior prognostic value of SUR in comparison to SUV in the first clinical studies. PMID: 30830508 [PubMed]
ConclusionThe present investigation demonstrates that the image-based manual determination of BSUV in the aorta is sufficiently reproducible across different observers and delineation tools which is a prerequisite for accurate SUR determination. This finding is in line with the already demonstrated superior prognostic value of SUR in comparison to SUV in the first clinical studies.
Conclusion: All 4 response criteria were highly predictive of OS, but visual criteria showed greater interobserver agreement and stronger discrimination between CMR and non-CMR, highlighting the importance of visual assessment to recognize radiation pneumonitis, changes in lung configuration, and patterns of response.
Condition: Lung Cancer Screening Intervention: Other: Low dose CT scan Sponsor: Centre Hospitalier d'Abbeville Recruiting
Abstract Objective: To determine whether 18F-fluorodeoxyglucose positron emission tomography/computed tomography performed immediately after percutaneous ablation (iPA18F-FDG PET/CT) is useful in evaluating the outcomes of the procedure. Materials and Methods: This was a retrospective study of 20 patients (13 males, 7 females; mean age, 65.8 ± 12.1 years) submitted to percutaneous ablation of metastases. All of the lesions treated had shown focal uptake on a 18F-FDG PET/CT scan obtained at baseline. The primary tumors were mainly colorectal cancer (in 45%) or lung cancer (in 40%). iPA18F-FDG PET/CT was performed to ...