Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment

ConclusionsAltogether, we show that tumor spheroids represent a relevant tool to study tumor-lymphocyte interactions on human tissues and revealed the antitumor potential of immunomodulatory antibodies targeting MICA/B and NKG2A.

http://link.springer.com/10.1186/s40425-019-0553-9

Source: Journal for Immunotherapy of Cancer - March 13, 2019 Category: Cancer & Oncology Source Type: research