A short introduction to vitamin K deficiency

(Natural News) A person needs vitamins, so his or her body can grow healthy and strong. For the most part, many people strive to include vitamin-rich foods in their diet: A healthy meal usually has all the vitamins that your body needs in a day, which include: Vitamin A B-vitamins (thiamine, riboflavin, niacin, pantothenic acid, folate,...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Authors: Kuwabara A, Nagae A, Kitagawa M, Tozawa K, Kumode M, Tanaka K Abstract We have previously reported that patients with severe motor and intellectual disabilities (SMID) have a high prevalence of vitamin K deficiency both in the liver and bone. Thus, vitamin K therapy for SMID patients should be considered. In the present study, we have studied the efficacy of nutritional therapy with vitamin K1 for improving their vitamin K status and bone metabolism markers in patients with SMID. During the 3-mo period, 19 patients under enteral feeding received vitamin K1 treatment, the dose of which was determined to mee...
Source: Journal of Nutritional Science and Vitaminology - Category: Nutrition Tags: J Nutr Sci Vitaminol (Tokyo) Source Type: research
AbstractUse of chronic vitamin K antagonist (VKA) induces a long-term deficiency of vitamin K, which may cause arterial stiffness and bone-related disease. Switching from VKA to rivaroxaban could induce rapid sufficiency of vitamin K and improvement of arterial stiffness. The K2 SUMMIT-3 study is a multicenter, open-label, prospective, and randomized design. Patients with atrial fibrillation who have been taking VKA for more than 6  months but less than 10 years were randomly assigned to two groups; those switching from VKA to rivaroxaban and those continuing with VKA medication. The primary endpoint was the perc...
Source: Heart and Vessels - Category: Cardiology Source Type: research
Scientists in Netherlands explore possible link between deficiency and Covid-19 deathsCoronavirus – latest updatesSee all our coronavirus coveragePatients who have died or been admitted to intensive care with Covid-19 have been found to be deficient in a vitamin found in spinach, eggs, and hard and blue cheeses, raising hopes that dietary change might be one part of the answer to combating the disease.Researchers studying patients who were admitted to the Canisius Wilhelmina hospital in the Dutch city of Nijmegen have extolled the benefits of vitamin K after discovering a link between deficiency and the worst coronav...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Coronavirus outbreak Netherlands Health Europe Infectious diseases Science Healthcare industry & wellbeing Source Type: news
CONCLUSIONS: There is very low-quality evidence of any effect of vitamin K in people with cystic fibrosis. While there is no evidence of harm, until better evidence is available the ongoing recommendations by national CF guidelines should be followed. PMID: 32497260 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Carlo Zambonin The absence of vitamin E from the diet can lead to cardiovascular disease, cancer, cataracts, and premature aging. Vitamin K deficiency can lead to bleeding disorders. These fat-soluble vitamins are important nutritional factors that can be determined in different methods in vegetables. In this work, the simultaneous determination of α-tocopherol, α-tocopheryl acetate, phylloquinone, and menaquinone-4 by gas chromatography–mass spectrometry (GC–MS) has been optimized using both direct injection and solid phase microextraction (SPME). Three different sample pre-t...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Protein C (PC) is a key component in the vitamin-K dependent coagulation pathway, which requires thrombin on the surface of endothelial cells to form activated PC. The latter exerts its anticoagulant effect by inhibiting both factors VIIIa and Va, thereby downregulating the coagulation pathways. A deficiency in plasma PC, therefore, results in a prothrombotic state. Heterozygous PC deficiency is estimated to occur in 0.02 –0.05% of the general population. It is discovered in 2–5% of incident and up to 10% of recurrent venous thromboembolic events [1].
Source: Thrombosis Research - Category: Hematology Authors: Tags: Letter to the Editors-in-Chief Source Type: research
Authors: Cacciapuoti F Abstract Dear Editor, Thrombophilia is the tendency to form blood clots both in arteries and veins [1]. Inherited and acquired high plasma homocysteine (HHcy) levels are judged as thrombophilic agents because can induce both arterial and venous thrombosis [2-5]. But, the association of hHHcy with Venous Thromboembolism (VTE) has been studied less extensively than that with arterial thrombosis. Some causes are responsible for this, such as Endothelial Dysfunction (ED). Several mechanisms have been suggested explaining HHcy-induced ED. Among these are included: nitric oxide (NO) inhibition due ...
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
An increase in serum undercarboxylated osteocalcin concentrations suggests vitamin K deficiency. Clinical intervention studies suggested that the vitamin K supplementation might contribute to preventing bone l...
Source: Journal of Physiological Anthropology - Category: Physiology Authors: Tags: Original article Source Type: research
We aimed to determine the presence of seasonal and meteorological associations of the activity of vitamin K-dependent coagulation factors to explain the seasonal variation in vitamin K deficiency-related bleeding. Seasonal and monthly changes in Normotest values in 1759 healthy 1-month-old infants were retrospectively accessed, and the impact of meteorological parameters on Normotest values was analyzed. Normotest values peaked in winter and were the lowest in summer, with statistically significant differences among the seasonal values (P 
Source: Blood Coagulation and Fibrinolysis - Category: Hematology Tags: SHORT COMMUNICATION Source Type: research
Nammacher MA, Willemin M, Hartmann JR, Gaston LW. Vitamin K deficiency in infants beyond the neonatal period. J Pediatr 1970;76:549-54.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Original Article Source Type: research
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