Using force-displacement relations to obtain actuation parameters from artificial muscles
Publication date: Available online 12 March 2019Source: Sensors and Actuators A: PhysicalAuthor(s): Geoffrey M. Spinks, Shannon E. Bakarich, Shazed Aziz, Bidita Salahuddin, Hai XinAbstractMany different test methods are currently used to characterise the output of artificial muscle materials but few studies report the full range of possible force and displacements that can be generated by a given material when activated with a given input stimulus but when operated against different external loads. The measurement of the loading and unloading force extension curves in tension in both the un-activated and activated states is investigated as a means for efficiently characterising the full range of outputs for three different types of artificial muscles: pneumatically operated braided muscle and thermally operated shape memory alloy spring and twisted / coiled polymer fiber. A graphical method of analysis was applied whereby the force-extension curves obtained before and after actuator activation were plotted on the same axes. By overlaying the external loading conditions, the graphical method provided the equilibrium starting and finishing forces and displacements and successfully predicted the isotonic strokes, isometric forces and combined force and displacement generated when the actuator was operated against an external spring. Complications in the interpretation of the force-stroke curves were encountered as all three artificial muscles displayed a degree of loading-unload...
Each year, approximately 265,000 Americans have a stroke that causes visual impairment. New research, which appears in the journal Proceedings of the Royal Society B, sheds light on how the damage in the brain caused by a stroke can lead to permanent vision impairment. The findings could provide researchers with a blueprint to better identify which areas of vision are recoverable, facilitating the development of more effective interventions to encourage vision recovery.
Zoltan Kiss, Gy örgy Rokszin, Zsolt Abonyi-Tóth, György Jermendy, Péter Kempler, István Wittmann
ConclusionIn patients suffering from severe CS due to AMI, the use of Impella is not associated with improved short-time survival but with higher complications rates compared to IABP and medical treatment. Better patient selection avoiding Impella implantation in futile situations or in possible lower risk CS might be necessary to elucidate possible advantages of Impella in future studies.
Abstract: Preeclampsia is a complication of pregnancy that affects approximately 4% of pregnancies. Preeclampsia is defined as new-onset hypertension after 20 weeks gestation often accompanied by new-onset proteinuria. Women who experience preeclampsia during pregnancy are at an increased risk for hypertension and stroke later in life. Healthcare providers should screen women appropriately to minimize risk.
Post-stroke depression has been previously associated with poorer recovery, but new research suggests depression may also be a risk factor for stroke.Medscape Medical News
The rate of older black and white people who receive Medicare benefits and die after an initial stroke has fallen over the last 25 years, a new study says.
Christine Smith, Mingxu Sun, Laurence Kenney, David Howard, Helen Luckie, Karen Waring, Paul Taylor, Earl Merson, Stacey Finn, Sarah Cotterill
Conclusions: Among stroke patients in ICU, we identified significant risk factors of stroke-associated AKI. Serum CysC level at ICU admission was an important biomarker for predicting AKI and 28-day mortality.Blood Purif
Publication date: Available online 19 March 2019Source: Journal of Critical CareAuthor(s): Luigi Vetrugno, Elena Bignami, Daniele Orso, Maria Vargas, Giovanni M. Guadagnin, Francesco Saglietti, Giuseppe Servillo, Giovanni Volpicelli, Paolo Navalesi, Tiziana BoveAbstractPurposeThe effects on the respiratory or hemodynamic function of drainage of pleural effusion on critically ill patients are not completely understood. First outcome was to evaluate the PiO2/FiO2 (P/F) ratio before and after pleural drainage. Secondary outcomes: evaluation of A-a gradient, End-Expiratory lung volume (EELV), heart rate (HR), mean arterial pre...
Publication date: Available online 19 March 2019Source: Pharmacological ResearchAuthor(s): Manish Kumar, Ritu Kulshrestha, Nirmal Singh, Amteshwar Singh JaggiAbstractImatinib is a tyrosine kinase inhibitor and is used as a first line drug in the treatment of Philadelphia-chromosome-positive chronic myeloid leukaemia and gastrointestinal stromal tumors. Being tyrosine kinase inhibitor, imatinib modulates the activities of Abelson gene (c-Abl), Abelson related gene (ARG), platelet-derived growth factor receptor (PDGFR), FMS-like tyrosine kinase 3 (FLT3), lymphocyte-specific protein (Lck), mitogen activated protein kinase (MA...