Severe ileocecal inflammatory syndrome in adult patients with cystic fibrosis.

We report on 2 adult patients with prior lung transplantation who presented with a severe inflammatory disorder of the ileocecal region. One patient underwent ileocecal resection; the second patient died after emergency surgery for intestinal perforation. Both cases did not show typical signs of CF-related distal intestinal obstruction syndrome or extensive fibrosing colonopathy. However, the clinical and histopathological findings revealed CF-induced inflammatory alterations of the intestinal mucosa. Thus, these cases illustrate a further CF-related bowel disorder, which can be especially relevant in long-term CF survivors.
PMID: 30861555 [PubMed - in process]

Source: Zeitschrift fur Gastroenterologie - February 28, 2019 Category: Gastroenterology Authors: Henker R, Oltmanns A, Wald A, Tuennemann J, Opitz S, Hoffmeister A, Wirtz H, Mössner J, Jansen-Winkeln B, Karlas T Tags: Z Gastroenterol Source Type: research