Human Paneth cell α-defensin 5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice.

CONCLUSION: This study provides proof-of-concept for the use of human defensins to improve host metabolism by mitigating the triad cluster of dyslipidemia, IR and NAFLD. PMID: 30860877 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30860877?dopt=Abstract

Source: Am J Physiol Endocri... - March 11, 2019 Category: Endocrinology Authors: Larsen IS, Fritzen AM, Carl CS, Agerholm M, Damgaard MTF, Holm JB, Marette A, Nordkild P, Kiens B, Kristiansen K, Wehkamp J, Jensen BAH Tags: Am J Physiol Endocrinol Metab Source Type: research