Combined endogenous and exogenous disinhibition of intracortical circuits augments plasticity induction in the human motor cortex

ConclusionsThis novel associative stimulation protocol augmented plasticity induction in the human motor cortex within a remarkably short period of time and in the absence of active movements. The combination of endogenous and exogenous disinhibition of intracortical circuits may provide a therapeutic backdoor when active movements are no longer possible, e.g., for hand paralysis after stroke.

Source: Brain Stimulation - March 13, 2019 Category: Neurology Source Type: research