Combined endogenous and exogenous disinhibition of intracortical circuits augments plasticity induction in the human motor cortex

ConclusionsThis novel associative stimulation protocol augmented plasticity induction in the human motor cortex within a remarkably short period of time and in the absence of active movements. The combination of endogenous and exogenous disinhibition of intracortical circuits may provide a therapeutic backdoor when active movements are no longer possible, e.g., for hand paralysis after stroke.
Source: Brain Stimulation - Category: Neurology Source Type: research

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Each year, approximately 265,000 Americans have a stroke that causes visual impairment. New research, which appears in the journal Proceedings of the Royal Society B, sheds light on how the damage in the brain caused by a stroke can lead to permanent vision impairment. The findings could provide researchers with a blueprint to better identify which areas of vision are recoverable, facilitating the development of more effective interventions to encourage vision recovery.
Source: University of Rochester Medical Center Press Releases - Category: Universities & Medical Training Authors: Source Type: news
Zoltan Kiss, Gy örgy Rokszin, Zsolt Abonyi-Tóth, György Jermendy, Péter Kempler, István Wittmann
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
ConclusionIn patients suffering from severe CS due to AMI, the use of Impella is not associated with improved short-time survival but with higher complications rates compared to IABP and medical treatment. Better patient selection avoiding Impella implantation in futile situations or in possible lower risk CS might be necessary to elucidate possible advantages of Impella in future studies.
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
Abstract: Preeclampsia is a complication of pregnancy that affects approximately 4% of pregnancies. Preeclampsia is defined as new-onset hypertension after 20 weeks gestation often accompanied by new-onset proteinuria. Women who experience preeclampsia during pregnancy are at an increased risk for hypertension and stroke later in life. Healthcare providers should screen women appropriately to minimize risk.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: WOMEN'S HEALTH: DNP SPECIAL ISSUE Source Type: research
Post-stroke depression has been previously associated with poorer recovery, but new research suggests depression may also be a risk factor for stroke.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
The rate of older black and white people who receive Medicare benefits and die after an initial stroke has fallen over the last 25 years, a new study says.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Christine Smith, Mingxu Sun, Laurence Kenney, David Howard, Helen Luckie, Karen Waring, Paul Taylor, Earl Merson, Stacey Finn, Sarah Cotterill
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusions: Among stroke patients in ICU, we identified significant risk factors of stroke-associated AKI. Serum CysC level at ICU admission was an important biomarker for predicting AKI and 28-day mortality.Blood Purif
Source: Blood Purification - Category: Hematology Source Type: research
Publication date: Available online 19 March 2019Source: Journal of Critical CareAuthor(s): Luigi Vetrugno, Elena Bignami, Daniele Orso, Maria Vargas, Giovanni M. Guadagnin, Francesco Saglietti, Giuseppe Servillo, Giovanni Volpicelli, Paolo Navalesi, Tiziana BoveAbstractPurposeThe effects on the respiratory or hemodynamic function of drainage of pleural effusion on critically ill patients are not completely understood. First outcome was to evaluate the PiO2/FiO2 (P/F) ratio before and after pleural drainage. Secondary outcomes: evaluation of A-a gradient, End-Expiratory lung volume (EELV), heart rate (HR), mean arterial pre...
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
Publication date: Available online 19 March 2019Source: Pharmacological ResearchAuthor(s): Manish Kumar, Ritu Kulshrestha, Nirmal Singh, Amteshwar Singh JaggiAbstractImatinib is a tyrosine kinase inhibitor and is used as a first line drug in the treatment of Philadelphia-chromosome-positive chronic myeloid leukaemia and gastrointestinal stromal tumors. Being tyrosine kinase inhibitor, imatinib modulates the activities of Abelson gene (c-Abl), Abelson related gene (ARG), platelet-derived growth factor receptor (PDGFR), FMS-like tyrosine kinase 3 (FLT3), lymphocyte-specific protein (Lck), mitogen activated protein kinase (MA...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
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