Global Influenza Strategy 2019 –2030

Source: World Health Organization (WHO). Published: 3/2019. Cited as the most comprehensive and far-reaching plan that the World Health Organization has ever developed for influenza, this 31-page strategy is aimed at protecting people in all countries from the threat of influenza, preventing seasonal influenza, controlling the spread of influenza from animals to humans, and preparing for the next influenza pandemic. It details how to build stronger country capacities for disease surveillance and response, prevention and control, and preparedness. Its Strategic Objective 4 is to strengthen pandemic preparedness and response for influenza to make the world safer. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news

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FRIDAY, Oct. 11, 2019 -- The risk for hospitalization with pandemic influenza is higher for patients with type 2 diabetes than for those without type 2 diabetes, according to a study published online Oct. 6 in the Journal of Internal Medicine. Paz...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Abstract Influenza viruses remain a severe burden to human health because of their contribution to overall morbidity and mortality. Current seasonal influenza virus vaccines do not provide sufficient protection to alleviate the annual impact of influenza and cannot confer protection against potentially pandemic influenza viruses. The lack of protection is due to rapid changes of the viral epitopes targeted by the vaccine and the often suboptimal immunogenicity of current immunization strategies. Major efforts to improve vaccination approaches are under way. The development of a universal influenza virus vaccine ma...
Source: Annual Review of Medicine - Category: General Medicine Authors: Tags: Annu Rev Med Source Type: research
In this study, we investigated the delivery of insect cell culture-derived recombinant hemagglutinin protein (HA) of A/H5N1/Vietnam/1203/2004 virus using CaPNP. We evaluated the vaccine immunogenicity in mice following two intramuscular doses of 3 μg antigen combined with escalating doses of CaPNP. Our data showed CaPNP-adjuvanted HA(H5N1) vaccines eliciting significantly higher IgG, hemagglutination inhibition, and virus neutralization titers compared to non-adjuvanted vaccine. Among the four adjuvant doses that were tested, CaPNP at 0.24% final concentration elicited the highest IgG and neutralizing antibody tite...
Source: AAPS PharmSciTech - Category: Drugs & Pharmacology Authors: Tags: AAPS PharmSciTech Source Type: research
This study illustrates how recurrent influenza infections increase the co-infection risk and facilitate evolutionary jumps by successive gene exchanges. It recalls the importance of appropriate biosecurity measures inside holdings to limit virus persistence and interspecies transmissi ons, which both contribute to the emergence of new potentially zoonotic viruses.
Source: Veterinary Research - Category: Veterinary Research Source Type: research
CONCLUSION: Although the concept of mandatory vaccination seems to be favoured by many health professionals in Europe, it remains a controversial subject both among HCWs' profession categories and also among different countries. Interventions to increase vaccination among HCWs would benefit by tailoring their approach according to disease and target group. PMID: 31580555 [PubMed - in process]
Source: Central European Journal of Public Health - Category: International Medicine & Public Health Tags: Cent Eur J Public Health Source Type: research
In this study, we aim to analyze the current evidence and findings associated with influenza and other emergent viral infections, namely, herpes simplex virus type 1 (HSV-1), Epstein-Barr virus (EBV), and cytomegalovirus (CMV).Among medical conditions, community-acquired respiratory infections are the most frequent reason for ventilatory support in ICUs. Community-acquired pneumonia in a severe form including the need of invasive mechanical ventilation and/or vasopressors is associated with high mortality rates. However, after the pandemic that occurred in 2009 by H1N1 influenza, the number of cases being admitted to ICUs ...
Source: Seminars in Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Review Article Source Type: research
When high schoolers in New York City were curious whether the sushi in their local market contained the kind of fish that was advertised, GenBank held the clues. When historians wanted to identify the sequence of the lethal pandemic 1918 influenza virus that killed millions worldwide, they found the answer through GenBank. When physicians were…
Source: NLM In Focus - Category: Databases & Libraries Authors: Tags: Programs & Services Source Type: blogs
Publication date: Available online 30 September 2019Source: The Lancet Respiratory MedicineAuthor(s): Richard T Davey, Eduardo Fernández-Cruz, Norman Markowitz, Sarah Pett, Abdel G Babiker, Deborah Wentworth, Surender Khurana, Nicole Engen, Fred Gordin, Mamta K Jain, Virginia Kan, Mark N Polizzotto, Paul Riska, Kiat Ruxrungtham, Zelalem Temesgen, Jens Lundgren, John H Beigel, H Clifford Lane, James D Neaton, Richard T DaveySummaryBackgroundSince the 1918 influenza pandemic, non-randomised studies and small clinical trials have suggested that convalescent plasma or anti-influenza hyperimmune intravenous immunoglobuli...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
This article evaluates the epidemiological evidence for a relationship between vaccination and neurological disease, specifically multiple sclerosis, Guillain –Barré syndrome and narcolepsy. The statistical methods used to test vaccine safety hypotheses are described and the merits of different study designs evaluated; these include the cohort, case-control, case-coverage and the self-controlled case-series methods. For multiple sclerosis, the evidence does not support the hypothesized relationship with hepatitis B vaccine. For Guillain−Barré syndrome, the evidence suggests a small elevated risk a...
Source: CNS Drugs - Category: Neurology Source Type: research
Influenza infection is considered to be a serious respiratory disease in human. Annually, epidemics or even pandemics give rise to the frequent antigenetic variations of virus surface receptors, throughout the world. Bacterial infections followed by influenza are the biggest medical concerns associated with elevated mortality rates. These high morbidity and mortality rates, have become a priority in terms of health. Likewise, economic aspects of the issue have special importance also. In the present study, several articles have been investigated with regards to main key words including influenza A, secondary bacterial inf...
Source: Reviews in Medical Microbiology - Category: Microbiology Tags: VIROLOGY Source Type: research
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