Fibroblast growth factor 21 deficiency aggravates obesity-induced hypothalamic inflammation and impairs thermogenic response

ConclusionsThese findings suggest that FGF21 deficiency aggravates obesity-induced hypothalamic inflammation and neuronal injury, leading to alterations in hypothalamic neural circuits accompanied by a reduction of the thermogenic response.

http://link.springer.com/10.1007/s00011-019-01222-2

Source: Inflammation Research - March 11, 2019 Category: Research Source Type: research