The Mitochondrial tRNAHis G12192A Mutation May Modulate the Clinical Expression of Deafness-Associated tRNAThr G15927A Mutation in a Chinese Pedigree.

CONCLUSION: Our data indicated that mt-tRNAHis G12192A mutation may increase the penetrance and expressivity of deafness-associated m-tRNAThr G15927A mutation in this family. PMID: 30854964 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30854964?dopt=Abstract

Source: Current Molecular Medicine - March 7, 2019 Category: Molecular Biology Authors: Ding Y, Teng YS, Zhuo GC, Xia BH, Leng JH Tags: Curr Mol Med Source Type: research