Glycosylation Profile of the Transferrin Receptor in Gestational Iron Deficiency and Early-Onset Severe Preeclampsia.

Conclusion: The increase in Gal-GlcNAc may be due to the increased presence of antennary structures and the mannose glycans of TfR1 may indicate the presence of misfolded or incomplete proteins. These findings may be associated with the low expression of placental TfR1 in women with preeclampsia.
PMID: 30854239 [PubMed - in process]

Source: Journal of Pregnancy - March 13, 2019 Category: OBGYN Tags: J Pregnancy Source Type: research