Establishment and characterization of a mouse model of rhabdomyolysis by coadministration of statin and fibrate.

In this study, a rhabdomyolysis mouse model was established by coadministration of the clinically using statin and fibrate. This mouse model may be useful to identify drugs that have high risk for rhabdomyolysis. PMID: 30853469 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30853469?dopt=Abstract

Source: Toxicology Letters - March 6, 2019 Category: Toxicology Authors: Watanabe K, Oda S, Matsubara A, Akai S, Yokoi T Tags: Toxicol Lett Source Type: research